BLERONE ^®

What to do if you missed your BLERONE ^® dose

Other known brand names

Detrusitol, Mariosea XL, Preblacon, Tolthen XL, Neditol XL, Detrol LA

About Blerone XL

Blerone XL contains tolterodine tartrate, an antimuscarinic (anticholinergic), as its active ingredient. It helps to reduce bladder muscle spasms and the urge to frequently urinate, caused by these spasms. Blerone XL is used to treat the symptoms of an overactive bladder, such as:

• Urinary urgency (a sudden and urgent need to pee)
• Urinary frequency (needing to pee more often than usual)
• Urinary incontinence (wetting yourself)
• Tolterodine relaxes muscles around your bladder, allowing your bladder to hold more liquid, stopping you from needing to pee as often or as urgently. It is available with a prescription as generic tolterodine or under brand names such as Blerone XL, Tolthen XL, Detrusitol, and Neditol XL.

NowPatient offers generic tolterodine or the branded treatments for urinary incontinence only, following an online consultation with a prescribing clinician.

Key facts of Blerone XL

• For the treatment of urinary incontinence
• Blerone XL starts to work within 3 to 8 hours but full effects may take up to 4 weeks to be seen
• Possible side effects of Blerone XL include dry mouth or headache
• It can be dangerous if you take Blerone XL with certain medications. If you’re not sure if it is safe, discuss this with the prescribing clinician
• You will normally take Blerone XL slow-release capsules once daily

Who is Blerone XL suitable for?

Tolterodine may be taken by adults. It may also be given to children 2 years of age and over, on specialist advice.

Who is Blerone XL not suitable for?

Blerone XL may not be suitable for some people. To make sure it’s safe for you, speak to the prescribing clinician before taking Blerone XL if you:

• Have had an allergic reaction to the active ingredient tolterodine
• Have urinary retention
• Have gastric retention
• Have renal impairment
• Have myasthenia gravis
• Have uncontrolled narrow-angle glaucoma
• Have a severe stomach or bowel condition
• Have toxic megacolon or ulcerative colitis
• Have any heart problems such as heart failure, long QT syndrome, or an irregular or slow heart rate (bradycardia)
• Have heartburn or acid reflux
• Have a hiatus hernia
• Have any nerve damage affecting blood pressure, heart rate, peeing and digestion (autonomic neuropathy)
• Are pregnant, trying to get pregnant or breastfeeding

How and where to get Blerone XL?

Blerone XL is available, only with a prescription. It is not available over the counter at a pharmacy.

NowPatient does not allow customers to buy Blerone XL directly. Our service is certified, safe and effective, and we only ever treat conditions. If you book a consultation with a prescribing clinician for the treatment of urinary incontinence, you can discuss if Blerone XL is a suitable treatment option for you.

At the end of the consultation, the clinician will decide if a treatment plan is suitable for you. If it is, the clinician will issue you with a prescription which can then be ordered, paid for and delivered directly to your chosen address by Now Patient.

Dosage and strength for Blerone XL for urinary incontinence

Tolterodine is available as immediate-release tablets, but is only available as Blerone XL 4 mg prolonged-release capsules when used for urinary incontinence.

Information about how to take Blerone XL for urinary incontinence

Blerone XL extended-release capsules should be taken whole with a glass of water, with or without food, at the same time each day. Do not chew, crush or break open the capsules.

If you are taking the extended-release capsules you will normally take 4mg once a day, unless you have liver or kidney problems, in which case you will take 2mg tablets once a day. For further information please speak to a healthcare professional for medical advice or read the patient information leaflet provided (PIL) with your medication.

What happens if you take too much Blerone XL?

If you take more than prescribed, then it can lead to some unpleasant side effects. You should talk to your doctor or reach out to one of our prescribing clinicians, if you have taken too much Blerone XL and you experience any of the following side effects:

What are the side effects of Blerone XL?

Side effects of Blerone XL are split into common and serious.

Common side effects include:

• Dry mouth
• Dry eyes
• Dry skin
• Headache
• Dizziness, drowsiness, blurred vision
• Gastrointestinal side effects such as diarrhoea, constipation, vomiting, burping, or passing wind, abdominal pain
• Palpitations

Serious side effects include:

• Faecal impaction
• Urinary retention
• Urinary tract infection (UTI)
• Swollen ankles or legs
• Angioedema – swollen face, throat or tongue, difficulty swallowing or breathing
• Disorientation

If you experience any serious side effects, you should contact NHS 111.

If you experience a serious allergic reaction with the signs shown below you should contact emergency services on 999.

• Your lips, mouth, throat or tongue suddenly become swollen
• You’re breathing very fast or struggling to breathe (you may become very wheezy or feel like you’re choking or gasping for air)
• Chest pain
• Your throat feels tight or you’re struggling to swallow
• Your skin, tongue or lips turn blue, grey or pale (if you have black or brown skin, this may be easier to see on the palms of your hands or soles of your feet)
• You suddenly become very confused, drowsy or dizzy
• Someone faints and cannot be woken up

Information about taking Blerone XL at the same time as other medications or herbal supplements

There may be drug interactions when using herbal remedies and supplements when taking Blerone XL. In any event, you should let your prescribing clinician know if you are taking any herbal supplements or other medicinal products, such as:

• Erythromycin or clarithromycin
• Ketoconazole or itraconazole
• Metoclopramide or cisapride
• Medication for irregular heartbeats such as amiodarone, sotalol, quinidine or procainamide
• Cyclosporine
• Vinblastine

Can Blerone XL taken for urinary incontinence be taken long term?

You should not take Blerone XL longer than you need to. Your doctor will check that you still need to take Blerone XL every 6 to 12 months.

Is there a herbal Blerone XL?

No. Herbal Blerone XL does not exist. If you have been marketed such a formulation, it may be fake.

Can women use Blerone XL?

Women can take Blerone XL, but it is not recommended in pregnancy or when breastfeeding. Speak to your doctor about taking Blerone XL if you’re pregnant, trying to get pregnant, or when breastfeeding.

Should I avoid any particular food or drink when taking Blerone XL?

You can eat and drink normally when taking Blerone XL. Some drinks may however irritate your bladder, making your symptoms worse. These include:

• Coffee, tea, cola and energy drinks
• Fizzy drinks
• Alcohol
• Diet drinks or those with artificial sweeteners
• Citrus, orange, grapefruit or lime juice

What lifestyle changes can I make to help me with urinary incontinence?

Modifying your lifestyle may have a positive impact on your urinary incontinence and quality of life. These may include:

• Pelvic floor muscle training to improve your bladder control
• Stay well hydrated to maintain a healthy urinary function
• Avoid caffeine, alcohol, and spicy foods
• Urinate when you feel the urge to
• When urinating, wait once you have finished for a few moments, and then try again to make sure the bladder is emptied completely

Alternatives to Blerone XL

Alternatives for the treatment of urinary incontinence include Betmiga, Yentreve and Emselex.

Sources

• Tolterodine – a medicine for treating symptoms of an overactive bladder – NHS
• Tolterodine: MedlinePlus Drug Information