ESTRADOT ^®

What to do if you missed your ESTRADOT ^® dose

Other known brand names

Estraderm, Evorel

About Estradot

Estradot patches are classed as a hormone replacement therapy (HRT). It contains estradiol, which acts in the same way as the female sex hormone oestrogen and is used to treat the symptoms of menopause.

If levels of oestrogen only are increased during HRT treatment, the endometrium would grow excessively, causing an increased risk of endometrial cancer. If you have not had a hysterectomy you will be prescribed a progestogen with Estradot.

Estradot helps to treat menopausal symptoms such as:

• Osteoporosis
• Hot flushes, night sweats
• Depression, mood swings
• Sleep problems
• Vaginal dryness

Now Patient offers Estradot patches as a treatment for HRT only, following an online consultation with a prescribing clinician.

Key facts of Estradot

• For the treatment of the symptoms of the menopause
• Estradot has some common side effects which include nausea and headaches
• Estradot will not prevent pregnancy in otherwise fertile women
• Do not use a hormonal contraceptive when treated with a HRT
• It can be dangerous if you use Estradot with certain medications. If you’re not sure if it is safe, discuss this with the prescribing clinician

Who is Estradot not suitable for?

Estradot may not be suitable for some people. To make sure it’s safe for you, speak to the prescribing clinician before using Estradot if you:

• Have hypersensitivity to the active ingredients estradiol
• Have ever had breast cancer
• Have cancer sensitive to oestrogen
• Have untreated endometrial hyperplasia (an excessively thick womb lining)
• Suffer from a blood clots
• Suffer from porphyria
• Have had a heart attack, angina, stroke, or high blood pressure
• Have unusual vaginal bleeding
• Have liver disease or any other liver problems
• Are pregnant or breastfeeding
• Have fibroids
• Have uterine problems such as endometriosis or endometrial hyperplasia
• Have diabetes
• Suffer from migraines
• Have gallbladder disease
• Have asthma
• Have epilepsy
• Have fluid retention
• Have high cholesterol levels in the blood
• Are obese
• Have a hereditary ear disorder

How and where to get Estradot?

Estradot patches are available with a prescription only. It is not available over the counter at a pharmacy.

Now Patient does not allow customers to buy Estradot patches directly. Our service is certified, safe and effective, and we only ever treat conditions. If you book a consultation with a prescribing clinician for the treatment of HRT, you can discuss if Estradot is a suitable treatment option for you.

At the end of the consultation, the clinician will decide if a treatment plan is suitable for you. If it is, the clinician will issue you with a prescription which can then be ordered, paid for and delivered directly to your chosen address by Now Patient.

Dosage and strength for Estradot patches for HRT

Estradot patches contain estradiol as the active ingredient. It is available as:

• Estradot 25 mcg/24hour patches containing 25 mcg per 24 hours of estradiol
• Estradot 37.5 mcg/24hour patches containing 37.5 mcg per 24 hours of estradiol
• Estradot 50 mcg/24hour patches containing 50 mcg per 24 hours of estradiol
• Estradot 75 mcg/24hour patches containing 75 mcg per 24 hours of estradiol
• Estradot 100 mcg/24hour patches containing 100 mcg per 24 hours of estradiol

Information about how to use Estradot for HRT

The Estradot patch should be applied to a clean and dry area of skin. You may choose to apply the patch to your thighs or bottom. The patch must be changed twice a week, on the same two days each week. You should not apply the new patch to the same area of skin and do not apply the patch around your breasts. Read the patient information leaflet provided or speak to a healthcare professional for further information. Use Estradot patches as directed by your doctor or pharmacist.

What happens if you use too much Estradot?

If you use more than prescribed, then it can lead to some unpleasant side effects. You should talk to your doctor or reach out to one of our prescribing clinicians, if you have used too much Estradot and you experience any of the following side effects:

What are the side effects of Estradot?

Side effects of Estradot are split into common and serious.

Common side effects include:

• Nausea
• Headache, dizziness
• Breast tenderness, breast pain
• Change in sex drive
• Anxiety, insomnia
• Stomach pain, indigestion, flatulence, diarrhoea
• Irregular bleeding
• Acne, skin irritation, rash
• Vaginal discharge
• Fluid retention, weight gain, bloating

Serious side effects include:

• Blood clots
• Stroke
• Heart disease – chest pain passing into the neck or arm
• Liver disease – jaundice (yellowing of the skin or eyes), abdominal pain

If you experience any serious side effects, you should contact NHS 111.

If you experience a serious allergic reaction with the signs shown below you should contact emergency services on 999.

• Your lips, mouth, throat or tongue suddenly become swollen
• You’re breathing very fast or struggling to breathe (you may become very wheezy or feel like you’re choking or gasping for air)
• Your throat feels tight or you’re struggling to swallow
• Your skin, tongue or lips turn blue, grey or pale (if you have black or brown skin, this may be easier to see on the palms of your hands or soles of your feet)
• You suddenly become very confused, drowsy or dizzy
• Someone faints and cannot be woken up

Always report adverse effects to the MHRA yellow card reporting system. You can read more about this here How and where do I report side effects of my medication? – NowPatient

Information about using Estradot at the same time as other medications or herbal supplements

There is not enough evidence to suggest there are any drug interactions between herbal supplements and Estradot. In any event, you should let your prescribing clinician know if you are taking any herbal supplements or other prescription drugs, such as:

• Phenytoin or carbamazepine
• Rifampicin
• Ritonavir or nelfinavir
• Warfarin
• St John’s Wort

Can Estradot used for HRT be used long term?

HRT should only be used as a short-term treatment for the menopause. Women who use HRT for more than 5 years may be at an increased risk of ovarian cancer. Speak to your GP to review your treatment at least once each year and have regular checkups.

Is there a herbal Estradot?

No. Herbal Estradot does not exist. If you have been marketed such a formulation, it may be fake.

Should I avoid any particular food or drink when using Estradot?

You can eat and drink normally when using Estradot.

What lifestyle changes can I make to help me with HRT?

You modify your lifestyle in a number of ways, and this may have a positive impact on your symptoms:

• Using a fan
• Cool showers
• Light clothing
• Lubricants
• Healthy diet
• Regular exercise
• Quit smoking

Alternatives to Estradot

Alternative HRT patches include Estaderm and Evorel.

Sources

• Menopause – Treatment – NHS
• Estradot.pdf